H-89PKA InhibitorPDF
Catalog Number:
E1B1643Amount:
PHYSICAL APPEARANCE: Off-white solid (m.p. 141-143°C)MOLECULAR FORMULA: C20H20BrN3O2S·2HCl
Molecular Weight:
519.2Purity:
99% (TLC: 10% Methanol/methylene chloride; Rf = 0.65)Storage/Stability:
Store solutions at -20°C for up to 1 year.Recommended Dilutions:
Potent, selective and widely used inhibitor of PKA (Ki = 48 nM). Cell permeable. Concentration range for cultured cells 30-100 μM: osteoblastic cells, renal proximal tubule cells and Xenopus oocytes.References:
1 T.Chijiwa et al. J.Biol.Chem. 1990 265 52672 M.Muroi and T.Suzuki Cell Signal 1993 5 2893 M.Fujihara et al. J.Biol.Chem. 1993 268 148984 A.Azarani et al. J.Biol.Chem. 1995 270 231665 A.Azarani et al. J.Biol.Chem. 1995 270 200046 A.Azarani et al. J.Biol.Chem. 1995 270 17898The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.Price:
40$