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商品描述
ForskolinPDF
Catalog Number:
E1B1612Amount:
PHYSICAL APPEARANCE: White solid, mp=229-232°CMOLECULAR FORMULA: C22H34O7
Molecular Weight:
410.5Purity:
99% (TLC)Storage/Stability:
Store solutions at -20°C for up to 1 year.Recommended Dilutions:
Activates adenylate cyclase by directly interacting with the catalytic subunit of the enzyme EC50=2-10 μM. Cell permeable and active in vivo. Most cell culture studies employ a working concentration of 5 or 10 μM. Do not make stock solutions in ethanol. Ethanol inhibits forskolin activation of adenylate cyclase. 1,9-Dideoxyforskolin may be used as a negative control.References:
1) Merck Index 13, 25002) Review K.B. Seamon Annu. Rep. Med. Chem. 1984 19 2933) K.B. Seamon and J.W. Daly Adv. Cyclic Nucl. Res. 1986 20 14) A. Laurenza et al. Trends Pharmacol. Sci. 1989 10 4425) N.J. De Souza et al. Med. Res. Rev. 1983 3 2016) R.D. Huang J. Cyclic Nucl. Res. 1982 8 385The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.Price:
50$
