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商品描述
15-PGDH Recombinant Protein
Product Code:
PSI-91-661
Pack Size:
0.05mg
Form:
Recombinant Protein
Storage Temp:
Store at -20˚C, stable for 6 months after receipt.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Target Species:
Human
Product Type:
Recombinant Proteins
Description:
15-hydroxyprostaglandin dehydrogenase [NAD(+)], also known as Prostaglandin dehydrogenase 1, 15-PGDH, HPGD and PGDH1, belongs to the short-chain dehydrogenases/reductases (SDR) family. HPGD localizes to the cytoplasm and can be found in colon epithelium, existing as a homodimer. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. HPGD is down-regulated by cortisol, dexamethasone and betamethasone, up-regulated by TGFB1. HPGD inhibits in vivo proliferation of colon cancer cells. HPGD is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation.
Source: Human Cells
Fusion Tag: C-6 His tag
Sequence: Met1-Gln266
Supplier:
ProSci
Product Category:
Proteins & Enzymes > Recombinant Proteins
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- Further Information
Product Code:
PSI-91-661 Price (0.05mg):
£667.00 excluding VAT
