ISHzymeforONCOREisadigestiveenzymeusedinthepretreatmentofformalin-fixedparaffin-embeddedtissues(FFPE)toenhanceprobeaccessibilitytonucleicacidtargets.InFFPEtissues,certaininsituhybridizationprotocolsrequireenzymaticpretreatmentforproperISHstaining.ISHzymeisanaggressiveenzymeandcanbeusedatroomtemperature.Certaintissuesrequirethistypeofaggressiveenzymedigestionpriortoheatretrievalforoptimalresults.WhenusedincombinationwithISHRetrievalforONCORE,asynergisticeffectonprobeaccessibilitytonucleicacidtargetsmaybeachieved.Thisproductisprovidedasatwo-componentsystemandmaybepreparedatvariousconcentrations,asdesiredbytheuser.
| Format | ONCORE |
|---|---|
| Volume | 120Tests |
| IntendedUse | IVD |
References:
1.WilkinsonDG.InSituHybridization:APracticalApproach(PracticalApproachSeries).2ndEd.Oxford:OxfordUniversityPress,1999.
2.NuovoGJ.InSituMolecularPathologyandCo-ExpressionAnalyses.1stEd.SanDiego:AcademicPress,2013.
3.ClinicalandLaboratoryStandardsInstitute(CLSI).ProtectionofLaboratoryWorkersfromOccupationallyAcquiredInfections;ApprovedGuideline-FourthEditionCLSIdocumentM29-A4Wayne,PA2014.
