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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
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https://www.ebiomall.com
商品描述
Product Description:BCA-1, CXCL13, human: CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. BCA-1 cDNA encodes a protein of 109 amino acid residues with a leader sequence of 22 residues. Mature human BCA-1 shares 64% amino acid sequence similarity with the mouse protein and 23 - 34% amino acid sequence identity with other known CXC chemokines. Recombinant or chemically synthesized BCA-1 is a potent chemoattractant for B lymphocytes but not T lymphocytes, monocytes or neutrophils. BLR1, a G protein-coupled receptor originally isolated from Burkitt’s lymphoma cells, has now been shown to be the specific receptor for BCA-1. Among cells of the hematopoietic lineages, the expression of BLR1, now designated CXCR5, is restricted to B lymphocytes and a subpopulation of T helper memory cells. Mice lacking BLR1 have been shown to lack inguinal lymph nodes. These mice were also found to have impaired development of Peyer’s patches and defective formation of primary follicles and germinal centers in the spleen as a result of the inability of B lymphocytes to migrate into B cell areas , UnitProt ID: O43927
Number of Containers:1
Refrigeration Requirements:Freezer
Shipping Conditions:ICE
UNSPSC Code:41116127
UNSPSC Category:Other Cytokines and Chemokines
Bio Basic（又称“ Bio Basic Group”和“ Bio Basic Canada”）于2004年在加拿大多伦多成立，最初是从其制造的生化试剂的分销开始的。继成功之后，Bio Basic从2008年开始迅速扩展其制造设施，包括寡核苷酸，基因和肽合成，DNA测序以及实验室塑料制品和分子生物学试剂盒等系列。从2009年起，Bio Basic通过引入蛋白质纯化和抗体合成来进一步扩展其服务范围，以完善其现有产品和服务。 
