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BioBasic/Amphotericin B/5g/AD0030P

价格
¥1740.80
货号:AD0030P
浏览量:127
品牌:BioBasic
服务
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商品描述
Product Description:Amphotericin B: Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. It has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. After binding to sterols, it forms channels in the membranes, causing small molecules to leak out. Amphotericin B is effective against fungi and yeast. The name of the drug is derived from the amphoteric behavior of the drug, due to the carboxyl group on the main ring and a primary amino group on the mycosamine ring. Amphotericin B induces K+ leakage, which is separate from its lethal action, as was demonstrated in human erythrocytes and is due to the inhibitory effect on the Na+/K+ pump. At sub-lethal concentrations, this drug stimulates either the activity of some membrane enzymes or cellular metabolism,3 in particular stimulation of some cells of the immune system. Minimum inhibitory concentrations range from 0.03–1 mg/ml for a variety of organisms including strains of Candida, Rhizopus, Asperigillus, and Coccidioides. It is inactive against bacteria, rickettsia, and viruses. Normal usage for maintenance of cell cultures is 2.5 mg/L with penicillin and streptomycin in the medium. For cultures already contaminated with yeast and fungus, use of this product at 2–4 times the normal level (5–10 mg/L), without penicillin and streptomycin for 2–3 subcultures is recommended. Once the contamination is under control, normal maintenance levels of amphotericin B should be used. Distilled water bath treatment is recommended for cleaning the incubator and for adding to the water reservoir to eliminate yeast and fungal contamination
Number of Containers:1
Refrigeration Requirements:Freezer
Shipping Conditions:ICE
UNSPSC Code:51101500
UNSPSC Category:Antibiotics and Antimycotics
Bio Basic(又称“ Bio Basic Group”和“ Bio Basic Canada”)于2004年在加拿大多伦多成立,最初是从其制造的生化试剂的分销开始的。继成功之后,Bio Basic从2008年开始迅速扩展其制造设施,包括寡核苷酸,基因和肽合成,DNA测序以及实验室塑料制品和分子生物学试剂盒等系列。从2009年起,Bio Basic通过引入蛋白质纯化和抗体合成来进一步扩展其服务范围,以完善其现有产品和服务。