BD Biosciences/Purified Mouse Anti-Human CD10/20 μL/347500

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¥5939.22
货号:347500
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品牌:BD Biosciences
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Description

The CD10 antibody, clone W8E7, is derived from the hybridization of P3-X63-Ag8.653 mouse myeloma cells with spleen cells of BALB/c mice immunized with blasts from a patient with non-T ALL.

The CD10 antibody (Anti-CALLA) recognizes a human common acute lymphoblastic leukemia antigen (CALLA), with a molecular weight of 100 kilodaltons (kDa). The CD10 antigen is identical to human membrane–associated neutral endopeptidase (NEP; EC 3.3.24.11), also known as enkephalinase.

Preparation and Storage

Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.

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  7. Le Bien TW, McCormack RT. The common acute lymphoblastic leukemia antigen (CD10): emancipation from a functional enigma. Blood. 1989;73:625-635.

  8. Letarte M, Vera S, Tran R, et al. Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase. J Exp Med. 1988;168:1247-1253.

  9. Loken MR, Shah VO, Dattilio KL, Civin CI. Flow cytometric analysis of human bone marrow. II. Normal B-lymphocyte development. Blood. 1987;70:1316-1324.

  10. Nadler LM, Korsmeyer SJ, Anderson KC, et al. B cell origin of non-T cell acute lymphoblastic leukemia: a model for discrete stages of neoplastic and normal pre-B cell differentiation. J Clin Invest. 1984;74:332-340.

  11. Zola H. CD10 Workshop Panel report. In: Schlossman SF, Boumsell L, Gilks W, et al, eds. Leucocyte Typing V: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1995:505-507.

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