快报
欢迎光临蚂蚁淘在线！ 请登录 免费注册
商品
品牌
文章
热门搜索：
快报
品牌首页 品牌新闻 品牌简介 产品中心 品牌咨询 联系我们
品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
蚂蚁淘在线 / 品牌中心 / BD Biosciences / BD Biosciences/FITC Mouse Anti-Human CD56/20 μL/340410

BD Biosciences/FITC Mouse Anti-Human CD56/20 μL/340410

价格
面议
货号：340410
浏览量：56
品牌：BD Biosciences
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Product DetailsRecommended AssayReferences

Description

The CD56 antibody, clone NCAM16.2, is derived from the hybridization of P3-X63-Ag8.653 mouse myeloma cells with spleen cells isolated from BALB/c mice immunized with immunoaffinity-enriched NCAM from detergent extracts of adult human brain.

The CD56 antibody recognizes a heavily glycosylated 140-kilodalton (kDa) isoform of NCAM, a member of the immunoglobulin (Ig) superfamily. The CD56 antibody also recognizes 180-kDa and 120-kDa isoforms of NCAM found in neurons and muscle, respectively.

Format
  • FormatFITC
  • Excitation SourceBlue 488 nm
  • Excitation Max494nm
  • Emission Max520nm

FITC, fluorescein isothiocyanate, is a fluorochrome with a molecular weight of 389 Da. FITC is sensitive to pH changes and photobleaching. Due to nearly identical excitation and emission properties but different spillover characteristics, FITC and Alexa Fluor® 488 cannot be used simultaneously. FITC is relatively dim and should be reserved for highly expressed markers whenever possible.

Resources & Tools
Spectrum ViewerPanel DesignerSpectrumViewerDownload TDSDownload MSDS
Preparation and Storage

Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.

  1. Protection of Laboratory Workers from Occupationally Acquired Infections; Approved Guideline—Third Edition. Wayne, PA: Clinical and Laboratory Standards Institute; 2005. CLSI document M29-A3.

  2. Campbell JJ, Qin S, Unutmaz D, et al. Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J Immunol. 2001;166:6477-6482.

  3. Centers for Disease Control. Perspectives in disease prevention and health promotion update: universal precautions for prevention of transmission of human immunodeficiency virus, hepatitis B virus, and other bloodborne pathogens in health-care settings. MMWR. 1988;37:377-388.

  4. Cooper MA, Fehniger TA, Caligiuri MA. The biology of human natural killer-cell subsets. Trends Immunol. 2001;22:633-640.

  5. Edelman GM. Cell adhesion molecules in the regulation of animal form and tissue pattern. Ann Rev Cell Biol. 1986;81:116.

  6. Galandrini R, Tassi I, Mattia G, et al. SH2-containing inositol phosphatase (SHIP-1) transiently translocates to raft domains and modulates CD16-mediated cytotoxicity in human NK cells. Blood. 2002;100:4581-4589.

  7. Gerosa F, Baldani-Guerra B, Nisii C, Marchesini V, Carra G, Trinchieri G. Reciprocal activating interaction between natural killer cells and dendritic cells. J Exp Med. 2002;195:327-333.

  8. Lanier LL, Chang C, Azuma M, Ruitenberg JJ, Hemperly JJ, Phillips JH. Molecular and functional analysis of human natural killer cell-associated neural cell adhesion molecule (N-CAM/CD56). J Immunol. 1991;146:4421-4426.

  9. Lanier LL, Le AM, Civin CI, Loken MR, Phillips JH. The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol. 1986;136:4480-4486.

  10. Lanier LL, Testi R, Bindl J, Phillips JH. Identity of the Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. J Exp Med. 1989;169:2233-2238.

  11. Nitta T, Yagita H, Sato K, Okumura K. Involvement of CD56 (NKH-1/Leu-19 antigen) as an adhesion molecule in natural killer–target cell interaction. J Exp Med. 1989;170:1757-1761.

  12. Phillips JH, Lanier LL. Dissection of the lymphokine-activated killer phenomenon: relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis. J Exp Med. 2002;195:327-333.

  13. Ritz J, Trinchieri G, Lanier LL. NK1 NK-cell antigens: section report. In: Schlossman SF, Boumsell L, Gilks W, et al, eds. Leucocyte Typing V: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1995;2:1367-1372.

  14. Zola H, Swart B, Nicholson I, Voss E. Leukocyte and Stromal Cell Molecules: The CD Markers. Hoboken, NJ: John Wiley & Sons, Inc.; 2007

BD Biosciences提供了广泛的试剂组合，用于研究细胞凋亡，细胞周期和细胞增殖。已经开发了几种方法来评估各种样品中的细胞凋亡，细胞周期和细胞增殖。我们的试剂可以探索这些过程的细胞特征。此外，BD Biosciences提供了多种工具来协助客户进行实验设置和分析。