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蚂蚁淘在线 / 品牌中心 / ApexBio / ApexBio/DiscoveryProbe™ Immunology/Inflammation-related Compounds Panel/5mg/well/L1010
商品描述
Related Products
- Bay 11-7085
- MLN120B
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- SC-514
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| DiscoveryProbe™ Immunology/Inflammation-related Compounds Panel |
Sample solution is provided at 25 µL, 10mM.
Click and Customize the Panelwith your own choices of compounds/size/quantities/chemical forms etc.
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| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles | |
| A3850 | TAK-242 | TLR 4 signaling inhibitor | Immunology/Inflammation|TLR | 243984-11-4 | CCOC(=O)C1=CCCCC1S(=O)(=O)NC2=C(C=C(C=C2)F)Cl | |
| A3248 | BMS-345541 | IKK inhibitor,highly selective | NF-κB|IκB/IKK | 547757-23-3 | CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN.Cl | |
| A3628 | MLN120B | IκB Kinase β Inhibitor | NF-κB|IκB/IKK | 783348-36-7 | CC1=C(C=CC=N1)C(=O)NC2=C3C(=CC(=C2OC)Cl)C4=C(N3)C=NC=C4 | |
| B1585 | SC-514 | ATP-competitive IKK-2 inhibitor, orally active | NF-κB|IκB/IKK | 354812-17-2 | C1=CSC=C1C2=CC(=C(S2)C(=O)N)N | |
| B3033 | Bay 11-7085 | NK-κB activation inhibitor | NF-κB|IκB/IKK | 196309-76-9 | CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)C=CC#N | |
| N1855 | Andrographolide | NF-κB signaling Inhibitor | NF-κB|IκB/IKK | 5508-58-7 | CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O | |
| A3891 | Triptolide | IL-2/MMP-3/MMP7/MMP19 inhibitor | NF-κB|NF-κB | 38748-32-2 | CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C | |
| A4217 | QNZ (EVP4593) | Potent NF-κB inhibitor | NF-κB|NF-κB | 545380-34-5 | C1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC3=NC=NC4=C3C=C(C=C4)N | |
| Download the Immunology/Inflammation-related Compounds Panel - XLSXDownload the Immunology/Inflammation-related Compounds Panel - SDF | ||||||
" to show IC50- Available in stock with overnight delivery and free shipping over $500
- Cost-effective and competitive price to save your findings
- Potent, selective and cell-permeable in inhibiting or activating target molecules
- Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
- Detailed files describing potency, selectivity and applications etc.
- Supported by published data from top peer-reviewed journals
- Guaranteed high quality with NMR and HPLC validation
| Solubility | Soluble in DMSO | Storage | Desiccate at -20°C |
| Packaging | 96 well plate | Form | Powder |
| General tips | For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue iceAll other available size:ship with RT , or blue ice upon request | ||
A wide range of well-characterized bioactive molecules that covers various targets related to immunology/inflammation, including TLR, PLA2 and NF-κB etc. Facilitate your research towards the insights of cancer, inflammatory and autoimmune diseases etc. Applicable in cellular assays, animal models and drug screenings etc.
1. Kawai T, Akira S. Toll-like receptors and their crosstalk with other innatereceptors in infection and immunity. Immunity. 2011 May 27;34(5):637-50.Abstract TLR(Toll-like receptor)-mediated recognition of components derived from a wide range of pathogens and their role in the subsequent initiation of innate immune responses is widely accepted; however, the recent discovery of non-TLR PRRs(pattern recognition receptors), such as C-type lectin receptors, NOD-like receptors, and RIG-I-like receptors, suggests that many aspects of innate immunity are more sophisticated and complex. In this review, we will focus on the role played by TLRs in mounting protective immune responses against infection and their crosstalk with other PRRs with respect to pathogen recognition.
