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蚂蚁淘在线 / 品牌中心 / ApexBio / ApexBio/DiscoveryProbe™ GPCR/G protein-related Compounds Panel/5mg/well/L1009
商品描述
Related Products
- Istradefylline (KW-6002)
- CP-945598 HCl
- SCH 527123
- AVE 0991
- Plerixafor (AMD3100)
- AM1241
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| DiscoveryProbe™ GPCR/G protein-related Compounds Panel |
Sample solution is provided at 25 µL, 10mM.
Click and Customize the Panelwith your own choices of compounds/size/quantities/chemical forms etc.
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| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles | |
| A8454 | Istradefylline (KW-6002) | Selective A2A receptor antagonist | GPCR/G protein|Adenosine Receptor | 155270-99-8 | CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)C=CC3=CC(=C(C=C3)OC)OC)C | |
| B1007 | AVE 0991 | Agonist of angiotensin-(1-7) receptor | GPCR/G protein|Angiotensin Receptor | 304462-19-9 | CCNC(=O)NS(=O)(=O)C1=C(C=C(S1)CC(C)C)C2=CC=C(C=C2)CN3C(=C(N=C3C4=CC=CC=C4)OC)C=O | |
| A1435 | CP-945598 HCl | CB1 antagonist,selective and high affinity | GPCR/G protein|Cannabinoid Receptor | 686347-12-6 | CCNC1(CCN(CC1)C2=NC=NC3=C2N=C(N3C4=CC=C(C=C4)Cl)C5=CC=CC=C5Cl)C(=O)N.Cl | |
| A5827 | AM1241 | Cannabinoid CB2 receptor agonist,potent and selective | GPCR/G protein|Cannabinoid Receptor | 444912-48-5 | CN1CCCCC1CN2C=C(C3=CC=CC=C32)C(=O)C4=C(C=CC(=C4)[N+](=O)[O-])I | |
| A2025 | Plerixafor (AMD3100) | CXCR4 antagonist; CXCR7 agonist | GPCR/G protein|CXCR | 110078-46-1 | C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3 | |
| A3802 | SCH 527123 | CXCR1 and CXCR2 receptors antagonist | GPCR/G protein|CXCR | 473727-83-2 | CCC(C1=CC=C(O1)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C | |
| B1633 | CTEP (RO4956371) | MGlu5 inhibitor | GPCR/G protein|mGluR | 871362-31-1 | CC1=C(N=C(N1C2=CC=C(C=C2)OC(F)(F)F)C)C#CC3=CC(=NC=C3)Cl | |
| A3616 | MK-4305 | OX1/OX2 atagonist,potent and selective | GPCR/G protein|OX Receptor | 1030377-33-3 | CC1CCN(CCN1C(=O)C2=C(C=CC(=C2)C)N3N=CC=N3)C4=NC5=C(O4)C=CC(=C5)Cl | |
| B2166 | Ticagrelor | P2Y12 receptor antagonist | GPCR/G protein|P2Y Receptor | 274693-27-5 | CCCSC1=NC2=C(C(=N1)NC3CC3C4=CC(=C(C=C4)F)F)N=NN2C5CC(C(C5O)O)OCCO | |
| Download the GPCR/G protein-related Compounds Panel - XLSXDownload the GPCR/G protein-related Compounds Panel - SDF | ||||||
Related Biological Data
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" to show IC50- Available in stock with overnight delivery and free shipping over $500
- Cost-effective and competitive price to save your findings
- Potent, selective and cell-permeable in inhibiting or activating target molecules
- Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
- Detailed files describing potency, selectivity and applications etc.
- Supported by published data from top peer-reviewed journals
- Guaranteed high quality with NMR and HPLC validation
| Solubility | Soluble in DMSO | Storage | Desiccate at -20°C |
| Packaging | 96 well plate | Form | Powder |
| General tips | For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue iceAll other available size:ship with RT , or blue ice upon request | ||
A wide range of well-characterized bioactive molecules that covers various targets related to GPCR, including adenosine receptor, adrenergic receptor and CXCR etc. Facilitate your research towards the insights of cancer, neurological disorders and heart diseases etc. Applicable in cellular assays, animal models and drug screenings etc.
1. Wettschureck N, Offermanns S. Mammalian G proteins and their cell typespecific functions. Physiol Rev. 2005 Oct;85(4):1159-204.Abstract G protein-mediated signaling is employed by virtually all cells in the mammalian organism and is centrally involved in diverse physiological functions such as perception of sensory information, modulation of synaptic transmission, hormone release and actions, regulation of cell contraction and migration, or cell growth and differentiation. In this review, some of the functions of heterotrimeric G proteins in defined cells and tissues are described.
