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ApexBio/Influenza A virus fragment/1mg/A1075

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¥5600.00
货号:A1075
浏览量:55
品牌:ApexBio
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Influenza A virus fragmentLeu-Lys-Phe-Ala-Phe-Ser-Met-Met

Catalog No.A1075
SizePriceStockQty
1mg
$40.00
In stock
5mg
$120.00
In stock
10mg
$200.00
In stock
25mg
$280.00
In stock

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Publications citing ApexBio Products

Nature.2017 Jan 19;541(7637):417-420.
Nature.2018 Nov;563(7731):407-411.
Nature.2018 Jun 13.
Nature.2018 Jun 27.
Nature.2018 Mar 29;555(7698):673-677.
Nature.2017 Sep 7;549(7670):96-100.
Nature.2016 Apr 21;532(7599):398-401.
Science.2016 Aug 5;353(6299)594-8
Nat Nanotechnol.2017 Dec;12(12):1190-1198.
Nature Biotechnology.2017 Jun;35(6):569-576
Nat Med.2018 Sep 17.
Cell.2018 Dec 21. pii: S0092-8674(18)31561-7.
Cell.Available online 25 October 2018.
Cell.2018 Sep 27. pii: S0092-8674(18)31183-8.
Cell.2018 Jun 28;174(1):172-186.e21.
Cell.2018 Feb 22;172(5):1007-1021.e17.
Cell.2017 Nov 30;171(6):1284-1300.e21.
Cell.2017 Aug 17. pii: S0092-8674(17)30869-3.
Cell.2017 Jul 13;170(2):312-323
Nat Med.2018 Jan 29.
Nat Med.2017 Nov;23(11):1342-1351.
Cell.2017 Apr 6;169(2):286-300.
Cell.2015 Aug 27;162(5):987-1002.
Cell.2015 Feb 12;160(4):729-44.
Nature Medicine.2017 Apr;23(4):493-500.
Cancer Cell.2018 May 14;33(5):905-921.e5.
Cancer Cell.2018 Apr 9;33(4):752-769.e8.
Cancer Cell.2018 Mar 12;33(3):401-416.e8.
Cancer Cell.2017 Aug 14;32(2):253-267.e5.
Nat Methods.2018 Jul;15(7):523-526.
Cell Stem Cell.2018 May 3;22(5):769-778.e4.
Cell Stem Cell.2017 Nov 20. pii: S1934-5909(17)30375-2.

Quality Control

Quality Control & MSDS

View current batch:
    Purity = 98.87%
  • COA (Certificate Of Analysis)
  • HPLC
  • MS (Mass Spectrometry)
  • MSDS (Material Safety Data Sheet)
  • Datasheet

Chemical structure

Influenza A virus fragment

Influenza A virus fragment Dilution Calculator

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Influenza A virus fragment Molarity Calculator

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Chemical Properties

Cas No. SDF Download SDF
Synonyms H2N-Leu-Lys-Phe-Ala-Phe-Ser-Met-Met-OH
Canonical SMILES CC(CC(C(NC(CCCCN)C(NC(CC1=CC=CC=C1)C(NC(C)C(NC(CC2=CC=CC=C2)C(NC(CO)C(NC(CCSC)C(NC(CCSC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)N)C
Formula C46H71N9O10S2 M.Wt 974.24
Solubility ≥88.7mg/mL in DMSO Storage Store at -20°C
Physical AppearanceA solidShipping ConditionEvaluation sample solution : ship with blue ice.All other available size:ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

Influenza A virus fragment has the RNA sequence of Leu-Lys-Phe-Ala-Phe-Ser-Met-Met.

Influenzavirus A is agenusof the Orthomyxoviridaefamily of viruses. Some isolatesof influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Influenza A viruses arenegative-sense, single-stranded, segmentedRNA viruses. The several subtypes are labeled according to an H number (for the type of hemagglutinin) and an N number (for the type ofneuraminidase).

The Influenza A virus genome is contained on eight single (non-paired) RNA strands that code for eleven proteins (HA, NA, NP, M1,M2, NS1, NEP, PA, PB1, PB1-F2, PB2).

A1075_1

Figure 1: Scheme of Influenza A virus

Ref:

1. "Avian influenza (" bird flu") — Fact sheet". WHO.

2. "Unique new flu virus found in bats". NHS Choices. 1 March 2012. Retrieved 16 May 2012.

3. Gewin, V. (2012). "Bats harbour influenza".Nature.

4. Tong, S.; Li, Y.; Rivailler, P.; Conrardy, C.; Castillo, D. A. A.; Chen, L. -M.; Recuenco, S.; Ellison, J. A. et al. (2012). "A distinct lineage of influenza a virus from bats".Proceedings of the National Academy of Sciences.

5. MicrobiologyBytes: Virology: Orthomyxoviruses

6. Subbarao, K.; Joseph, T. (2007). “Scientific barriers to developing vaccines against avian influenza viruses”. Nature Reviews Immunology 7, 267-278.

ApexBio的3X FLAG Peptide FLAG标签系统利用与目标蛋白质1融合的短而亲水的8个氨基酸的肽段。FLAG肽与抗体M1结合。结合是钙依赖性方式2还是非依赖性3仍存在争议。该系统的缺点是单克隆抗体纯化基质不如其他基质稳定。通常,可以用特异性单克隆抗体检测小标签。为了改善对FLAG标签的检测,已经开发了3x FLAG系统。这种三级FLAG表位是亲水的,长22个氨基酸,可以检测到高达10 fmol的表达融合蛋白。激烈热球菌的带有FLAG标签的麦芽糖糊精结合蛋白已被结晶4,其晶体质量与未标记蛋白的晶体质量非常相似。 最后,可以通过用肠激酶处理去除FLAG标签,肠激酶对肽序列5的5个C末端氨基酸具有特异性。