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Advanced immunochemical/SARS-CoV-2 Nucleoprotein, recombinant/1mg/8-CoVnp

价格
¥8300.00
货号:8-CoVnp
浏览量:127
品牌:Advanced immunochemical
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商品描述

General Category:

    Antigens
      Antigens » Infectious Diseases

Disease Category:

    Antigens
      Antigens » Infectious Diseases
Source:
Expressed in E. coli
Description:
Nucleoprotein is a full-length SARS-CoV-2 nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2] GenBank: QHD43423.2. Contains C-terminal GS linker and His10-tag. Theoretical MW 47141 Da including GS linker and His10-tag Theoretical pI: 10.07
Applications:
Antigen for detection of anti-(SARS-CoV-2 nucleocapsid protein) antibodies
Analysis:
Purity > 95%Concentration is determined spectrophotometrically at A280
Purification:
Metal affinity chromatography
Presentation:
Lyophilized 20 mM Tris-HCl, 500 mM NaCl, pH 8.0. It is recommended to reconstitute this product with deionized water to its initial concentration.
Other Information:
Avoid repeated freezing and thawing. It is recommended to aliquot the product after reconstitution.
Storage Conditions:
Lyophilized and reconstituted at -20°C (-15 … -30 °C allowed)
Material safety note:
This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.
Advanced immunochemical高敏C反应蛋白人C反应蛋白(CRP)是所谓的急性期蛋白之一。它在血液中的浓度随着对炎症的反应而迅速增加。CRP是224个残基蛋白,单体分子量约为25 kDa,pI 6.4(1-4)。它属于五味子毒素,这是一种进化保守的蛋白质家族,其特征在于钙依赖性配体结合和五个单体的对称性,这些单体在中心孔周围形成一个环(5)。CRP在体内的确切功能尚不完全清楚。已证明CRP参与炎症以及先天免疫过程。CRP的重要生物活性取决于其与各种配体(例如受损细胞膜,凋亡细胞和纤连蛋白)的结合能力,对磷胆碱残基的亲和力最高。当CRP与配体结合时,它可以被补体成分C1q识别,从而激活经典补体途径。另一方面,CRP通过与补体因子H相互作用来调节替代补体途径