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Advanced immunochemical/Monoclonal mouse anti- insulin-like growth factor-binding protein-5 (IGFBP-5)/0.2 mg/2-IGFBP5

价格
¥9660.00
货号:2-IGFBP5
浏览量:127
品牌:Advanced immunochemical
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商品描述

General Category:

    Monoclonal antibodies » Tumor Markers

Disease Category:

    Tumor Markers » Monoclonal antibodies
MAbs:
IBPF12, IBPF16, IBPF20, IBPF87Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with human IGFBP-5 recombinant fragment expressed in E. coli corresponding to amino acid residues Lys164-Glu272 (MAb IBPF87), synthetic peptide from human IGFBP-5 corresponding to amino acid residues Cys100-Glu120 (MAbs IBPF12 and IBPF16) or synthetic peptide from human IGFBP-5 corresponding to amino acid residues Ser125-Ile144 (MAb IBPF20).
Specificity:
Human IGFBP-5
MAb Isotypes:
IgG1 for MAbs IBPF12, IBPF16, IBPF20IgG2a for MAb IBPF87
Applications:
All MAbs work in direct ELISA and Western Blotting.Recommended pairs for IGFBP-5 immunodetection in sandwich immunoassay (capture-detection):IBPF12 – IBPF87IBPF16 – IBPF20 MAbIBPF16 works in IGFBP-5 immunoprecepitation.MAbs IBPF16 and IBPF87 can be used for immunoaffinity purification.
Purification:
Chromatography on protein A Sepharose
Presentation:
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
Storage Conditions:
+ 4 °C
Other information:
Some applications in which these products may be used are covered by patents issued and applicable in certain countries. Because purchase of these products does not include a license to perform any patented application, users of these products may be required to obtain a patent license, depending on the particular application and country in which the product is used.
Material Safety Note:
This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material.Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Advanced immunochemical高敏C反应蛋白人C反应蛋白(CRP)是所谓的急性期蛋白之一。它在血液中的浓度随着对炎症的反应而迅速增加。CRP是224个残基蛋白,单体分子量约为25 kDa,pI 6.4(1-4)。它属于五味子毒素,这是一种进化保守的蛋白质家族,其特征在于钙依赖性配体结合和五个单体的对称性,这些单体在中心孔周围形成一个环(5)。CRP在体内的确切功能尚不完全清楚。已证明CRP参与炎症以及先天免疫过程。CRP的重要生物活性取决于其与各种配体(例如受损细胞膜,凋亡细胞和纤连蛋白)的结合能力,对磷胆碱残基的亲和力最高。当CRP与配体结合时,它可以被补体成分C1q识别,从而激活经典补体途径。另一方面,CRP通过与补体因子H相互作用来调节替代补体途径