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Advanced immunochemical/Monoclonal mouse anti-human alpha-fetoprotein/0.2 mg/2-AFP1

价格
¥4040.00
货号:2-AFP1
浏览量:104
品牌:Advanced immunochemical
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商品描述

General Category:

    Monoclonal antibodies » Tumor Markers

Disease Category:

    Fertility and PregnancyTumor Markers » Monoclonal antibodies
MAbs:
5H7, 4A3Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified human alpha-fetoprotein.
Specificity:
MAbs react with different determinants of human alpha-fetoprotein.MAbs do not cross-react with human albumin.
MAb Isotypes:
IgG1 for MAb 5H7IgG2a for MAb 4A3
Applications:
We recommend the following pair in sandwich immunoassay (capture-detection): 4A3 – 5H7
Purification:
Chromatography on protein A Sepharose
Presentation:
PBS, pH 7.4, 0.9 % sodium azide (NaN3)
Storage Conditions:
+ 4 °C
Material Safety Note:
This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material.Contains sodium azide (0.1 % or 0.05%) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Advanced immunochemical高敏C反应蛋白人C反应蛋白(CRP)是所谓的急性期蛋白之一。它在血液中的浓度随着对炎症的反应而迅速增加。CRP是224个残基蛋白,单体分子量约为25 kDa,pI 6.4(1-4)。它属于五味子毒素,这是一种进化保守的蛋白质家族,其特征在于钙依赖性配体结合和五个单体的对称性,这些单体在中心孔周围形成一个环(5)。CRP在体内的确切功能尚不完全清楚。已证明CRP参与炎症以及先天免疫过程。CRP的重要生物活性取决于其与各种配体(例如受损细胞膜,凋亡细胞和纤连蛋白)的结合能力,对磷胆碱残基的亲和力最高。当CRP与配体结合时,它可以被补体成分C1q识别,从而激活经典补体途径。另一方面,CRP通过与补体因子H相互作用来调节替代补体途径