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Advanced immunochemical/Glial fibrillary acidic protein (GFAP)/0.1 mg/8-GFAP-h

价格
¥9440.00
货号:8-GFAP-h
浏览量:80
品牌:Advanced immunochemical
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商品描述

General Category:

    Antigens » Neuroscience

Disease Category:

    Neuroscience » Antigens
Source:
Human brain.Blood sample from the tissue donor was tested and found negative for HbsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis.
Analysis:
Purity > 90 % (SDS-PAGE).GFAP preparations are represented by several 43-49 kDa protein bands. The major two bands appear in the region of 46 kDa.
Immunological activity:
Verified in ELISA using anti-GFAP antibodies.
Purification:
Two-staged tissue extraction, hydroxyapatite chromatography
Presentation:
Presentation: Lyophilized from 16 mM NaHCO3, pH 8.5.Product is recommended to reconstitute with distilled water.
Storage Conditions:
-20 °C (between -15 and -30 °C allowed)
Material safety note:
This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.
Advanced immunochemical高敏C反应蛋白人C反应蛋白(CRP)是所谓的急性期蛋白之一。它在血液中的浓度随着对炎症的反应而迅速增加。CRP是224个残基蛋白,单体分子量约为25 kDa,pI 6.4(1-4)。它属于五味子毒素,这是一种进化保守的蛋白质家族,其特征在于钙依赖性配体结合和五个单体的对称性,这些单体在中心孔周围形成一个环(5)。CRP在体内的确切功能尚不完全清楚。已证明CRP参与炎症以及先天免疫过程。CRP的重要生物活性取决于其与各种配体(例如受损细胞膜,凋亡细胞和纤连蛋白)的结合能力,对磷胆碱残基的亲和力最高。当CRP与配体结合时,它可以被补体成分C1q识别,从而激活经典补体途径。另一方面,CRP通过与补体因子H相互作用来调节替代补体途径