ACROBiosystems/Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (AS86)/1mg/S2N

价格
¥52000.00
货号:S2N
浏览量:127
品牌:ACROBiosystems
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商品描述
  • Source
    Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (AS86) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from CHO cells.
  • Isotype
    Human IgG4/kappa
  • Specificity
    This product is a specific antibody against SARS-CoV-2 Spike S2 protein. Cross-reactivity with S2 protein of other coronaviruses has not been tested.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH6.0. Normally trehalose is added as protectant before lyophilization.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20 to -70°C for 12 months in lyophilized state from date of receipt;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (Cat. No. S2N-S86) SDS-PAGE gel

Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA
Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (Cat. No. S2N-S86) ELISA bioactivity

Immobilized SARS-CoV-2 S2 protein, His Tag (Cat. No. S2N-C52H5) at 2 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (Cat. No. S2N-S86) with a linear range of 0.12-2 ng/mL (QC tested).

Protocol
  • Background
    The ongoing SARS-COV-2 pandemics has sickened 3.7 million people around the world, claiming over 1,000,000 lives. To deal with this global public health crisis, unprecedented efforts are being made to study the virus, SARS-CoV-2. At present, there are 193 new crown vaccine projects registered with the World Health Organization are being developed. To support these studies, ACRO has developed Mouse Anti-SARS-CoV-2 antibody IgG Serologic Assay kit.
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

ACROBiosystems治疗性抗体的功效不仅取决于Fab片段及其与靶抗原的结合活性,还取决于Fc片段及其与关键Fc受体的相互作用。Fc片段对FcRn的结合亲和力(FCGRT&B2M)将预测抗体的半衰期,而Fc片段与FcγRIIIa(CD16a)之间的结合亲和力将影响抗体引发ADCC的能力(抗体依赖性细胞介导的细胞毒性)。因此,必须在抗体工程化过程中针对一组受体测试候选人。ACROBiosystems提供了完整的重组Fc受体蛋白集合,包括它们的常见变体,以帮助您加快mAb的开发。