BaseScope™ Detection Reagents- RED are based on ACD"s patented signal amplification and background suppression technology. This high sensitive RNA ISH technique and can be used for short targets, splice variants and point mutations (coming soon). The BaseScope™ Detection Reagents include the Fast Red dye offers a higher contrast and is the first choice in situ hybridization applications where chromogenic staining with DAB is less desirable, such as staining of highly pigmented lung, liver, retina and melanoma tissue specimens. Also for genes where a lower expression is expected ACD recommends this assay as the red dots clearly distinguish against the hematoxylin staining and are visible under are standard brightfield microscope.