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Abeomics/Z-IE(OMe)TD(OMe)-FMK (Caspase 8 Inhibitor)/FMK (Caspase 8 Inhibitor) 1 mg/15-2005

价格
¥7000.00
货号:15-2005
浏览量:127
品牌:Abeomics
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商品描述

Amount :5 mg
Content :Yellow solid
Storage condition :Store at -20°C.

Molecular Weight: 654Formula: C30H43N4O11FMass Spec: M+1=655.1 TLC: EtOAc: 100%, Rf:0.3NMR: All functional groups are present

SOLUBILITY:Prepare the stock solution of 20 mM in DMSO. Aliquot the stock solution and store it in -20°C.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Abeomics的人PD-L1重组Fc融合蛋白(正在供货)CHO-K1 Celline。 PD-L1(CD274 / B7-H1)是一种重要的膜结合共刺激分子,属于B7超家族,可通过其受体抑制免疫反应,PD-1和PD-L1在炎症性疾病的发病机理中起关键作用死亡1)。它在单核吞噬细胞系统(MPS)中广泛表达,可共同刺激T细胞并调节炎症反应。PD-L1通过对T细胞功能产生负面共刺激作用来发挥炎症调节功能,以抑制细胞因子分泌,促进活化T细胞凋亡并诱导T细胞无反应。在细菌感染,炎症和许多自身免疫性疾病中,已经报道了CD274的异常表达和失调。