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Abeomics/Boc-D(OMe)-FMK (Pan Caspase Inhibitor)/1 mg/15-2004

价格
¥5000.00
货号:15-2004
浏览量:127
品牌:Abeomics
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商品描述

Amount :5 mg
Content :White Semi-Solid
Storage condition :Store at -20°C

Molecular Weight: 263Formula: C11H18FNO5Mass Spec: M+1=468.2TLC: Single-Spot (EtOAc: Hexane, 3.7) : Rf:0.5 NMR: All functional groups are present

SOLUBILITY:Prepare the stock solution of 20 mM in DMSO. Aliquot the stock solution and store it in -20°C

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Abeomics的人PD-L1重组Fc融合蛋白(正在供货)CHO-K1 Celline。 PD-L1(CD274 / B7-H1)是一种重要的膜结合共刺激分子,属于B7超家族,可通过其受体抑制免疫反应,PD-1和PD-L1在炎症性疾病的发病机理中起关键作用死亡1)。它在单核吞噬细胞系统(MPS)中广泛表达,可共同刺激T细胞并调节炎症反应。PD-L1通过对T细胞功能产生负面共刺激作用来发挥炎症调节功能,以抑制细胞因子分泌,促进活化T细胞凋亡并诱导T细胞无反应。在细菌感染,炎症和许多自身免疫性疾病中,已经报道了CD274的异常表达和失调。