| Amount : | 10 mg |
| Purification : | ≥98% |
| Content : | Paritaprevir is supplied as a solid. |
| Storage condition : | Store at -20°C, product is stable for at least two years. |
| Alternative Name : | ABT-450 |
Molecular Formula:C40H43N7O7S
Molecular Weight:765.9
Paritaprevir is an orally bioavailable, direct-acting inhibitor of the hepatitis C virus (HCV) non-structural 3/4A (NS3/4A) serine protease.It inhibits HCV replication in stable Huh7-derived replicon cell lines infected with subgenomic genotypes 1a, 1b, 2a, 3a, 4a, and 6a (EC50s = 1, 0.21, 5.3, 19, 0.09, and 0.69 nM, respectively). It also inhibits replicons from clinical isolates of genotypes 1a (EC50s = 0.43-1.87 nM) and 1b (EC50s = 0.033-0.087 nM). Formulations containing paritaprevir in combination with ombitasvir, ritonavir, and dasabuvir with and without ribavirin have been used in the treatment of chronic HCV genotype 1 infection.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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