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Abeomics/Rabbit Monoclonal Antibody to PD1(Clone :BSR1)/0.1 ml/10-12513

价格
面议
货号:10-12513
浏览量:116
品牌:Abeomics
服务
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签订合同
商品描述

Gene :PDCD1
Gene ID :5133
Uniprot ID :Q15116
Alternative Name :CD279
Format :concentrate
Amount :0.5 ml
Content :TRIS with 0.03% sodium azide, pH7.2
Storage condition :Store at 4°C

Immunohistochemical Analysis :-1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:Membrane
BioGrid:111160.61 interactions.
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Abeomics的人PD-L1重组Fc融合蛋白(正在供货)CHO-K1 Celline。 PD-L1(CD274 / B7-H1)是一种重要的膜结合共刺激分子,属于B7超家族,可通过其受体抑制免疫反应,PD-1和PD-L1在炎症性疾病的发病机理中起关键作用死亡1)。它在单核吞噬细胞系统(MPS)中广泛表达,可共同刺激T细胞并调节炎症反应。PD-L1通过对T细胞功能产生负面共刺激作用来发挥炎症调节功能,以抑制细胞因子分泌,促进活化T细胞凋亡并诱导T细胞无反应。在细菌感染,炎症和许多自身免疫性疾病中,已经报道了CD274的异常表达和失调。