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蚂蚁淘在线 / 品牌中心 / Abeomics / Abeomics/Mouse Monoclonal Antibody to CD22(Clone :BS100)/0.1 ml/10-12509

Abeomics/Mouse Monoclonal Antibody to CD22(Clone :BS100)/0.1 ml/10-12509

价格
￥9120.00
货号：10-12509
浏览量：127
品牌：Abeomics
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商品描述
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Format :concentrate
Amount :0.5 ml
Content :TRIS with 0.03% sodium azide, pH7.2
Storage condition :Store at 4°C
Gene :CD22
Gene ID :933
Uniprot ID :P20273
Alternative Name :B-lymphocyte cell adhesion molecule, Sialic acid-binding Ig-like lectin 2, T-cell surface antigen Leu-14, SIGLEC2

Immunohistochemical Analysis :-1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:Cell membrane
Post transnational modification:Phosphorylated on tyrosine residues by LYN.
Tissue Specificity:B-lymphocytes.
BioGrid:107371.15 interactions.
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Abeomics的人PD-L1重组Fc融合蛋白（正在供货）CHO-K1 Celline。 PD-L1（CD274 / B7-H1）是一种重要的膜结合共刺激分子，属于B7超家族，可通过其受体抑制免疫反应，PD-1和PD-L1在炎症性疾病的发病机理中起关键作用死亡1）。它在单核吞噬细胞系统（MPS）中广泛表达，可共同刺激T细胞并调节炎症反应。PD-L1通过对T细胞功能产生负面共刺激作用来发挥炎症调节功能，以抑制细胞因子分泌，促进活化T细胞凋亡并诱导T细胞无反应。在细菌感染，炎症和许多自身免疫性疾病中，已经报道了CD274的异常表达和失调。