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商品描述
HPV (IN) (Human Papillomavirus), E7 protein
Human Papillomavirus 116; E7 protein
Download Product PDFProduct Preparation
A synthetic peptide corresponding to the internal sequence of human papillomavirus type 16.
Background
The strain of Human papilloma virus 16 (HPV16 or E7 protein) is directly linked to cervical cancer and can be diagnosed with a colposcopy and biopsy. Human papilloma virus is one of the most common causes of sexually transmitted infection in the world.E7 protein has transforming and trans-activating activities that are known to disrupt the function of host retinoblastoma protein (Rb1). E6 is a transcriptional trans-activator with transforming activities targeting p53 tumor suppressor. HPV16, in comparison to HPV types 6 and 11, is more often associated with malignant genital cancers in humans. This antibody was raised in rabbit against protein E7 of human papillomavirus type 16 (HPV16) whichis mainly used for research on sexually-transmitted diseases and gynecology tumor.
PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification | SPECIFICITY This antibody recognizes ~40 kDa of HPV16/E7-GST recombinant protein. The other species are not tested. |
FORMULATION This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
8223418
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry 5-10µg/ml |
