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0512-67156496
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商品描述
Rictor (phospho-Thr1135)rabbit pAb
- Catalog No.:YP1466
- Applications:WB
- Reactivity:Human,Mouse
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name:
- RICTOR KIAA1999
- Protein Name:
- Rictor (Thr1135)
- Human Gene Id:
- 253260
- Human Swiss Prot No:
- Q6R327
- Mouse Gene Id:
- 78757
- Mouse Swiss Prot No:
- Q6QI06
- Immunogen:
- Synthesized phosho peptide around human Rictor (Thr1135)
- Specificity:
- This antibody detects endogenous levels ofHuman Mouse Rictor (phospho-Thr1135)
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Rabbit
- Dilution:
- WB 1:1000-2000
- Purification:
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -20°C/1 year
- Other Name:
- Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
- Observed Band(KD):
- 190
- Background:
- RPTOR independent companion of MTOR complex 2(RICTOR) Homo sapiensRICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008],
- Function:
- function:Plays an essential role in embryonic growth and development (By similarity). Part of the TORC2 complex which plays a critical role in AKT1 "Ser-473" phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.,similarity:Belongs to the pianissimo family.,subunit:Forms part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to FRAP1 and PROTOR1 within the TORC2 complex. May interact with PROTOR2.,
- Subcellular Location:
- cytosol,TORC2 complex,
- Expression:
- Amygdala,Brain,Epithelium,Lymph,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- June 19-2018
- FLOW CYTOMEYRT PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs