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Immunoway/Rictor (phospho-Thr1135) rabbit pAb/20ug 50ug 100ug/YP1466

价格
¥1700.00
货号:YP1466
浏览量:127
品牌:Immunoway
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商品描述

Rictor (phospho-Thr1135)rabbit pAb

  • Catalog No.:YP1466
  • Applications:WB
  • Reactivity:Human,Mouse
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name:
    • RICTOR KIAA1999
    • Protein Name:
    • Rictor (Thr1135)
    • Human Gene Id:
    • 253260
    • Human Swiss Prot No:
    • Q6R327
    • Mouse Gene Id:
    • 78757
    • Mouse Swiss Prot No:
    • Q6QI06
    • Immunogen:
    • Synthesized phosho peptide around human Rictor (Thr1135)
    • Specificity:
    • This antibody detects endogenous levels ofHuman Mouse Rictor (phospho-Thr1135)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:1000-2000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
    • Observed Band(KD):
    • 190
    • Background:
    • RPTOR independent companion of MTOR complex 2(RICTOR) Homo sapiensRICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008],
    • Function:
    • function:Plays an essential role in embryonic growth and development (By similarity). Part of the TORC2 complex which plays a critical role in AKT1 "Ser-473" phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.,similarity:Belongs to the pianissimo family.,subunit:Forms part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to FRAP1 and PROTOR1 within the TORC2 complex. May interact with PROTOR2.,
    • Subcellular Location:
    • cytosol,TORC2 complex,
    • Expression:
    • Amygdala,Brain,Epithelium,Lymph,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。