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Immunoway/Acetyl eIF5A/eIF5A2 (K47) Polyclonal Antibody/50ug 100ug/YK0021

价格
¥3800.00
货号:YK0021
浏览量:23
品牌:Immunoway
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商品描述

    Acetyl eIF5A/eIF5A2 (K47) Polyclonal Antibody

    • Catalog No.:YK0021
    • Applications:WB,ELISA
    • Reactivity:Human,Mouse,Rat
    • Data Sheet
    • MSDS
    • Support
    • Description
    • References ( 0 )
    • Protocol
      • Gene Name:
      • EIF5A2
      • Protein Name:
      • Eukaryotic translation initiation factor 5A-2
      • Human Gene Id:
      • 56648
      • Human Swiss Prot No:
      • Q9GZV4
      • Mouse Gene Id:
      • 208691
      • Mouse Swiss Prot No:
      • Q8BGY2
      • Immunogen:
      • The antiserum was produced against synthesized Acetyl-peptide derived from human eIF5A around the Acetylation site of Lys47. AA range:11-60
      • Specificity:
      • Acetyl-eIF5A/eIF5A2 (K47) Polyclonal Antibody detects endogenous levels of eIF5A/eIF5A2 protein only when acetylated at K47.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Western Blot: 1/500 - 1/2000.ELISA: 1/20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • EIF5A2; Eukaryotic translation initiation factor 5A-2; eIF-5A-2; eIF-5A2; Eukaryotic initiation factor 5A isoform 2
      • Background:
      • function:The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.,PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).,similarity:Belongs to the eIF-5A family.,tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.,
      • Function:
      • function:The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.,PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).,similarity:Belongs to the eIF-5A family.,tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.,
      • Subcellular Location:
      • nuclear pore,endoplasmic reticulum membrane,cytosol,intracellular membrane-bounded organelle,
      • Expression:
      • Brain,Epithelium,Ovarian carcinoma,
      • June 19-2018
      • WESTERN IMMUNOBLOTTING PROTOCOL
      • June 19-2018
      • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
      • June 19-2018
      • IMMUNOFLUORESCENCE PROTOCOL
      • September 08-2020
      • FLOW-CYTOMEYRT-PROTOCOL
      • July 13-2018
      • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
      • July 13-2018
      • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
      • July 13-2018
      • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
      • July 13-2018
      • Antibody-FAQs
      • Products Images
      • Western blot analysis of L929 lysis using antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Western blot analysis of lysate from L929 cells, using eIF5A (Acetyl-Lys47) Antibody.
      Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。