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Immunoway/Adenosine A3-R Polyclonal Antibody/50ug 100ug/YT0132

价格
¥3200.00
货号:YT0132
浏览量:127
品牌:Immunoway
服务
全国联保
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商品描述

    Adenosine A3-R Polyclonal Antibody

    • Catalog No.:YT0132
    • Applications:WB,IHC-p,IF/ICC,ELISA
    • Reactivity:Human
    • Data Sheet
    • MSDS
    • Support
    • Description
    • References ( 0 )
    • Protocol
      • Gene Name:
      • ADORA3
      • Protein Name:
      • Adenosine receptor A3
      • Human Gene Id:
      • 140
      • Human Swiss Prot No:
      • P33765
      • Mouse Swiss Prot No:
      • Q61618
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human ADORA3. AA range:269-318
      • Specificity:
      • Adenosine A3-R Polyclonal Antibody detects endogenous levels of Adenosine A3-R protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • ADORA3; Adenosine receptor A3
      • MolecularWeight(Da):
      • 36185
      • Observed Band(KD):
      • 38
      • Background:
      • adenosine A3 receptor(ADORA3) Homo sapiensThis gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014],
      • Function:
      • function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.,PTM:Phosphorylation on Ser-317 may be crucial for rapid desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,
      • Subcellular Location:
      • plasma membrane,integral component of membrane,
      • Expression:
      • Adrenal gland,Brain,Heart,Lung,Testis,
      • June 19-2018
      • WESTERN IMMUNOBLOTTING PROTOCOL
      • June 19-2018
      • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
      • June 19-2018
      • IMMUNOFLUORESCENCE PROTOCOL
      • September 08-2020
      • FLOW-CYTOMEYRT-PROTOCOL
      • July 13-2018
      • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
      • July 13-2018
      • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
      • July 13-2018
      • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
      • July 13-2018
      • Antibody-FAQs
      • Products Images
      • Western Blot analysis of various cells using Adenosine A3-R Polyclonal Antibody
      • Western Blot analysis of MCF7 cells using Adenosine A3-R Polyclonal Antibody
      • Immunofluorescence analysis of COS7 cells, using ADORA3 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from HepG2 cells, using ADORA3 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from 293 cells using ADORA3 antibody.
      Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。