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Immunoway/ARHGAP12 Polyclonal Antibody/50ug 100ug/YT0315

价格
¥3200.00
货号:YT0315
浏览量:127
品牌:Immunoway
服务
全国联保
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商品描述

ARHGAP12 Polyclonal Antibody

  • Catalog No.:YT0315
  • Applications:WB,ELISA
  • Reactivity:Human,Mouse,Rat
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name:
    • ARHGAP12
    • Protein Name:
    • Rho GTPase-activating protein 12
    • Human Gene Id:
    • 94134
    • Human Swiss Prot No:
    • Q8IWW6
    • Mouse Gene Id:
    • 75415
    • Mouse Swiss Prot No:
    • Q8C0D4
    • Immunogen:
    • Synthesized peptide derived from ARHGAP12 . at AA range: 310-390
    • Specificity:
    • ARHGAP12 Polyclonal Antibody detects endogenous levels of ARHGAP12 protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • ARHGAP12; Rho GTPase-activating protein 12; Rho-type GTPase-activating protein 12
    • MolecularWeight(Da):
    • 96254
    • Observed Band(KD):
    • 100
    • Background:
    • Rho GTPase activating protein 12(ARHGAP12)Homo sapiensThis gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
    • Function:
    • function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 WW domains.,
    • Subcellular Location:
    • cytosol,
    • Expression:
    • PCR rescued clones,Placenta,T-cell,Testis,Uterus,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • September 08-2020
    • FLOW-CYTOMEYRT-PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。