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商品描述
TACC3 (phospho-Ser558)rabbit pAb
- Catalog No.:YP1521
- Applications:WB
- Reactivity:Human
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name:
- TACC3 ERIC1
- Protein Name:
- TACC3 (Ser558)
- Human Gene Id:
- 10460
- Human Swiss Prot No:
- Q9Y6A5
- Mouse Swiss Prot No:
- Q9JJ11
- Immunogen:
- Synthesized phosho peptide around human TACC3 (Ser558)
- Specificity:
- This antibody detects endogenous levels ofHuman TACC3 (phospho-Ser558)
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Rabbit
- Dilution:
- WB 1:1000-2000
- Purification:
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -20°C/1 year
- Other Name:
- Transforming acidic coiled-coil-containing protein 3 (ERIC-1)
- Observed Band(KD):
- 80
- Background:
- transforming acidic coiled-coil containing protein 3(TACC3) Homo sapiensThis gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011],
- Function:
- function:Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May be involved in the control of cell growth and differentiation. May contribute to cancer.,induction:Up-regulated in various cancer cell lines.,similarity:Belongs to the TACC family.,subunit:Interacts with microtubules. Interacts with CCDC100/CEP120. The coiled coil C-terminus region interacts with AH receptor nuclear translocator protein (ARNT) and ARNT2 (By similarity). Interacts with GCN5L2 and PCAF.,
- Subcellular Location:
- spindle pole,cytoplasm,microtubule organizing center,microtubule cytoskeleton,
- Expression:
- Epithelium,PCR rescued clones,Skin,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- June 19-2018
- FLOW CYTOMEYRT PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs