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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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https://www.ebiomall.com
商品描述
YAP (phospho-Ser109) rabbit pAb
- Catalog No.：YP1553
- Applications：WB
- Reactivity：Human,Mouse,Rat
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- YAP1 YAP65
- Protein Name：
- YAP (Ser109)
- Human Gene Id：
- 10413
- Human Swiss Prot No：
- P46937
- Mouse Gene Id：
- 22601
- Mouse Swiss Prot No：
- P46938
- Rat Gene Id：
- 363014
- Rat Swiss Prot No：
- Q2EJA0
- Immunogen：
- Synthesized phosho peptide around human YAP (Ser109)
- Specificity：
- This antibody detects endogenous levels ofHuman Mouse Rat YAP (phospho-Ser109)
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Rabbit
- Dilution：
- WB 1:1000-2000
- Purification：
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- Yorkie homolog (65 kDa Yes-associated protein) (YAP65)
- Observed Band(KD)：
- 67
- Background：
- Yes associated protein 1(YAP1)Homo sapiensThis gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],
- Function：
- PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 WW domain.,subunit:Binds to the SH3 domain of the YES kinase. Binds to WBP1 and WBP2. Binds, in vitro, through the WW1 domain, to neural isoforms of ENAH that contain the PPSY motif.,
- Subcellular Location：
- nucleus,nucleoplasm,transcription factor complex,cytoplasm,cytosol,membrane,
- Expression：
- Epithelium,Human spinal cord,Lung,Pancreas,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- June 19-2018
- FLOW CYTOMEYRT PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
