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4000-520-616 / 18915418616
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0512-67156496
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商品描述
Rev-erbα (phospho-Ser55/59) rabbit pAb
- Catalog No.：YP1465
- Applications：WB
- Reactivity：Human
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- NR1D1 EAR1 HREV THRAL
- Protein Name：
- Rev-erbα (Ser55/59)
- Human Gene Id：
- 9572
- Human Swiss Prot No：
- P20393
- Mouse Gene Id：
- 217166
- Mouse Swiss Prot No：
- Q3UV55
- Rat Gene Id：
- 252917
- Rat Swiss Prot No：
- Q63503
- Immunogen：
- Synthesized phosho peptide around human Rev-erbα (Ser55 and 59)
- Specificity：
- This antibody detects endogenous levels ofHuman Rev-erbα (phospho-Ser55 or 59)
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Rabbit
- Dilution：
- WB 1:1000-2000
- Purification：
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha) (V-erbA-related protein 1) (EAR-1)
- Observed Band(KD)：
- 67
- Background：
- nuclear receptor subfamily 1 group D member 1(NR1D1)Homo sapiensThis gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013],
- Function：
- domain:Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain.,function:Functions as a constitutive transcriptional repressor. Possible receptor for triiodothyronine.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with C1D.,tissue specificity:Expressed in all tissues and cell lines examined. Expressed at high levels in some squamous carcinoma cell lines.,
- Subcellular Location：
- nuclear chromatin,nucleus,nucleoplasm,cytoplasm,dendrite,dendritic spine,
- Expression：
- Epithelium,Fetal skeletal muscle,Placenta,PNS,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- June 19-2018
- FLOW CYTOMEYRT PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
