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蚂蚁淘在线 / 品牌中心 / Immunoway / Immunoway/β-Arrestin 1 (phospho-Ser412) rabbit pAb/20ug 50ug 100ug/YP1557
商品描述
β-Arrestin 1 (phospho-Ser412) rabbit pAb
- Catalog No.：YP1557
- Applications：WB
- Reactivity：Human,Mouse,Rat
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- ARRB1 ARR1
- Protein Name：
- β-Arrestin 1 (Ser412)
- Human Gene Id：
- 408
- Human Swiss Prot No：
- P49407
- Mouse Gene Id：
- 109689
- Mouse Swiss Prot No：
- Q8BWG8
- Rat Gene Id：
- 25387
- Rat Swiss Prot No：
- P29066
- Immunogen：
- Synthesized phosho peptide around human β-Arrestin 1 (Ser412)
- Specificity：
- This antibody detects endogenous levels ofHuman Mouse Rat β-Arrestin 1 (phospho-Ser412)
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Rabbit
- Dilution：
- WB 1:1000-2000
- Purification：
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- Beta-arrestin-1 (Arrestin beta-1)
- Observed Band(KD)：
- 47
- Background：
- arrestin beta 1(ARRB1)Homo sapiensMembers of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],
- Function：
- function:Regulates beta-adrenergic receptor function. Beta-arrestins seem to bind phosphorylated beta-adrenergic receptors, thereby causing a significant impairment of their capacity to activate G(S) proteins.,online information:Arrestin entry,similarity:Belongs to the arrestin family.,
- Subcellular Location：
- Golgi membrane,chromatin,nucleus,nucleoplasm,cytoplasm,lysosomal membrane,cytosol,heterotrimeric G-protein complex,plasma membrane,clathrin-coated pit,postsynaptic density,basolateral plasma membrane,cytoplasmic vesicle membr
- Expression：
- Brain,Peripheral blood,Uterus,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- June 19-2018
- FLOW CYTOMEYRT PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
