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蚂蚁淘在线 / 品牌中心 / Immunoway / Immunoway/VEGF Receptor 2 (phospho-Tyr996) rabbit pAb/20ug 50ug 100ug/YP1550
商品描述
VEGF Receptor 2 (phospho-Tyr996) rabbit pAb
- Catalog No.：YP1550
- Applications：WB
- Reactivity：Human,Mouse
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- KDR FLK1 VEGFR2
- Protein Name：
- VEGF Receptor 2 (Tyr996)
- Human Gene Id：
- 3791
- Human Swiss Prot No：
- P35968
- Mouse Swiss Prot No：
- P35918
- Rat Gene Id：
- 25589
- Rat Swiss Prot No：
- O08775
- Immunogen：
- Synthesized phosho peptide around human VEGF Receptor 2 (Tyr996)
- Specificity：
- This antibody detects endogenous levels ofHuman Mouse VEGF Receptor 2 (phospho-Tyr996)
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Rabbit
- Dilution：
- WB 1:1000-2000
- Purification：
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
- Observed Band(KD)：
- 150
- Background：
- kinase insert domain receptor(KDR)Homo sapiensVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009],
- Function：
- catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi"s sarcoma lesions.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 7 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with MYOF (By similarity). Interacts with SHB; upon VEGF activation. Interacts with HIV-1 Tat.,
- Subcellular Location：
- extracellular region,nucleus,endosome,early endosome,endoplasmic reticulum,Golgi apparatus,plasma membrane,integral component of plasma membrane,integral component of membrane,cytoplasmic, membrane-bounded vesicle,cell junction,
- Expression：
- Aorta endothelial cell,Lung,Umbilical vein,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- June 19-2018
- FLOW CYTOMEYRT PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
