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Immunoway/CD82 Polyclonal Antibody/20ug 50ug 100ug/YN0174

价格
¥1400.00
货号:YN0174
浏览量:66
品牌:Immunoway
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商品描述

CD82 Polyclonal Antibody

  • Catalog No.:YN0174
  • Applications:WB,ELISA
  • Reactivity:Human
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name:
    • CD82 KAI1 SAR2 ST6 TSPAN27
    • Protein Name:
    • CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)
    • Human Gene Id:
    • 3732
    • Human Swiss Prot No:
    • P27701
    • Mouse Swiss Prot No:
    • P40237
    • Rat Swiss Prot No:
    • O70352
    • Immunogen:
    • Synthesized peptide derived from human protein . at AA range: 120-200
    • Specificity:
    • CD82 Polyclonal Antibody detects endogenous levels of protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol,and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:500-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Observed Band(KD):
    • 29
    • Background:
    • CD82 molecule(CD82) Homo sapiensThis metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
    • Function:
    • function:Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.,similarity:Belongs to the tetraspanin (TM4SF) family.,subunit:Interacts directly with IGSF8.,tissue specificity:Lymphoid specific.,
    • Subcellular Location:
    • plasma membrane,integral component of plasma membrane,integral component of membrane,extracellular exosome,
    • Expression:
    • Liver,Peripheral blood lymphocyte,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。