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Immunoway/TWIK-2 Polyclonal Antibody/20ug 50ug 100ug/YT4787

价格
¥1400.00
货号:YT4787
浏览量:127
品牌:Immunoway
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商品描述

TWIK-2 Polyclonal Antibody

  • Catalog No.:YT4787
  • Applications:WB,ELISA
  • Reactivity:Human
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name:
    • KCNK6
    • Protein Name:
    • Potassium channel subfamily K member 6
    • Human Gene Id:
    • 9424
    • Human Swiss Prot No:
    • Q9Y257
    • Immunogen:
    • Synthesized peptide derived from TWIK-2 . at AA range: 240-320
    • Specificity:
    • TWIK-2 Polyclonal Antibody detects endogenous levels of TWIK-2 protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • KCNK6; TOSS; TWIK2; Potassium channel subfamily K member 6; Inward rectifying potassium channel protein TWIK-2; TWIK-originated similarity sequence
    • MolecularWeight(Da):
    • 33747
    • Observed Band(KD):
    • 33
    • Background:
    • potassium two pore domain channel subfamily K member 6(KCNK6) Homo sapiensThis gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics. [provided by RefSeq, Jul 2008],
    • Function:
    • function:Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions.,miscellaneous:Inhibited by internal acidification and, to a small degree, by zinc. Not inhibited by quinine, quinidine or barium.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,tissue specificity:Widespread expression, detected in all tissues tested except for skeletal muscle. Strongest expression in placenta, pancreas, heart, colon and spleen, lower levels detected in peripheral blood leukocytes, lung, liver, kidney and thymus. Lowest expression detected in brain.,
    • Subcellular Location:
    • plasma membrane,voltage-gated potassium channel complex,integral component of membrane,
    • Expression:
    • Brain,Breast,Coronary artery,Pancreas,Testis,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway角蛋白8(KRT8)智人该基因是II型角蛋白家族的一个成员,聚集在12号染色体的长臂上。I型和II型角蛋白在上皮细胞的细胞质中杂聚形成中等大小的细丝。该基因的产物通常与角蛋白18聚合,在简单的单层上皮细胞中形成中间丝。该蛋白在维持细胞结构完整性中起作用,并且还在信号转导和细胞分化中起作用。该基因的突变会导致隐源性肝硬化。已经发现该基因的剪接的转录变体。