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4000-520-616 / 18915418616
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0512-67156496
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商品描述
Claudin 2 mouse mAb(PT0311)
- Catalog No.：YM4159
- Applications：IHC-p,WB
- Reactivity：Human
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- CLDN2 PSEC0059 SP82 UNQ705/PRO1356
- Protein Name：
- Claudin 2
- Human Gene Id：
- 9075
- Human Swiss Prot No：
- P57739
- Immunogen：
- Synthesized peptide derived from human Claudin 2
- Specificity：
- This antibody detects endogenous levels of human Claudin 2
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Mouse/IgG2b, Kappa
- Dilution：
- IHC-p 1:100-300，WB 1:500-2000
- Purification：
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- Claudin-2 (SP82)
- Background：
- claudin 2(CLDN2)Homo sapiensThis gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010],
- Function：
- function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
- Subcellular Location：
- plasma membrane,bicellular tight junction,integral component of membrane,extracellular exosome,
- Expression：
- Colon,Colon epithelium,Kidney,Skin,Teratocarcinoma,Thalamus,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- June 19-2018
- FLOW CYTOMEYRT PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
