CatalogNo.: K-5300 Description: Echelon’sHeparinELISAisaquantitativeimmunoassaydesignedforinvitromeasurementofheparininpurified/syntheticsamples. | |||
ProductBackground:Heparinisahighlysulfatedglycosaminoglycanranginginsizefrom6to20kDa.Heparinispresentedinmastcell,liverandlungs.Althoughitsfunctionisunknown,itiswidelyusedasananticoagulanttopreventbloodclottinginvivoandinvitro.Forexample,heparinisusedaspreventativetreatmentfordeepveinthrombosisandpulmonaryembolism.Oversulfatedchondroitinsulfatecontaminationinrawheparinstocksusedforinjectableheparinmanufacturingwasdiscoveredin2008andresultedinamajorrecallofrelatedmedicalproducts.AccordingtotheFDA,itisbelievedatleast11deathswereassociatedwiththecontaminatedheparin-containingdevicesworldwide.Therefore,ensuringpurityofrawhepariniscriticalinmedicalheparinmanufacturing. Storage4°CReferencesCai,S.etal."ASelectiveProteinSensorforHeparinDetection."AnalBiochem.326(1),33-41(2004). |