品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com

EagleBio/easYmer HLA-A*30:02 MHC Tetramers Kit/1031-01

价格
面议
货号:1031-01
浏览量:127
品牌:EagleBio
服务
全国联保
正品保证
正规发票
签订合同
商品描述

easYmer HLA-A*30:02 MHC Tetramers Kit

easYmer HLA-A*30:02 MHC Tetramers Kit Developed and Manufactured by immunAware

Materials Included:

The easYmer kit contains a peptide receptive preparation of HLA, a folding buffer, a positive control peptide for HLA-complex folding. The exact identities of these components are given below:

  • easYmer: HLA-A*30:02 – peptide receptive and biotinylated HLA-A*30:02 molecules in Tris/Maleate pH7 with 30% Glycerol
  • Folding Buffer: Tris/Maleate pH7
  • Peptide: YF NS5 286-295 (KSEYMTSWFY), a known HLA-A*30:02 binder. Positive control for evaluation analysis of peptide-HLA folding

for Research Use Only

Available Sizes:

  • 20 Tests (Sample-size)
  • 50 Tests (Standard Size)
  • 150 Tests
  • 500 Tests

Key Benefits of easYmer® MHC Tetramers

  • Ready-to-use
  • One step loading
  • Completely flexible and customizable*
  • Biotinylated
  • No special equipment needed
  • Long shelf-life

*For Custom Tetramer Production, please Contact Us for more information


Assay Principle

This protocol is designed to evaluate the efficiency of peptide-HLA-I interaction and complex formation. The assay is based on detecting the ß2-microglobulin (ß2m? light chain subunit of recombinant HLA Class I (HLA-I) comlexes, where the heavy chain has been biotin tagged. These tagged complexes are subsequently captured by streptavidin coated beads, labeled with PE-conjugated anti-human ß2m, and analyzed by flow cytometry. Since peptide-HLA-I complex formation is entirely peptide dependent, bead-associated signals will only be detected if the peptide in question supports the folding of the HLA-I allotype of interest; peptides that efficiently support folding will give strong signals whereas peptides that support folding sub-optimally, or not at all, will give moderate to non-detectable signals.


Products Related to easYmer HLA-A*30:02 MHC Tetramers

easYmer HLA-A*36:01 MHC Tetramers Kit
easYmer HLA-A*68:01 MHC Tetramers Kit
easYmer HLA-A*68:02 MHC Tetramers Kit

EagleBio的5α-雄甾烷-3α,17β-二醇葡糖醛酸化物是C19类固醇,缩写为3α-DiolG,5α二醇G或简称为α二醇G。它主要作为睾丸激素和二氢睾丸激素(DHT)的代谢产物生产。它主要在目标外围组织(例如皮肤)中产生,尤其是在毛囊周围。大量的3α-DiolG刺激会导致过多的头发形成,特别是在女性通常不存在头发的地方。近年来,在研究患有特发性多毛症的妇女的临床研究人员中,人们对这种类固醇的测量越来越感兴趣。已知是3α-DiolG前体的类固醇包括脱氢表雄酮(DHEA),硫酸脱氢表雄酮(DHEAS),二氢睾丸酮(DHT),雄烯二酮和睾丸激素。已显示只有3α-DiolG随多毛症增加而随治疗减少。这种相关性在多囊卵巢综合征(PCO)患者中也得到了证明。3α-DiolG的测定因此被证明是多种方式的有用指标,包括监测特发性多毛症和PCO妇女的治疗进展。此外,接受环孢霉素A治疗的糖尿病患者(无论男女)均显示3α-DiolG水平升高,这种副作用导致以前无毛的区域出现了头发。3α-DiolG的测定因此被证明是多种方式的有用指标,包括监测特发性多毛症和PCO妇女的治疗进展。此外,接受环孢霉素A治疗的糖尿病患者(无论男女)均显示3α-DiolG水平升高,这种副作用导致以前无毛的区域出现了头发。3α-DiolG的测定因此被证明是多种方式的有用指标,包括监测特发性多毛症和PCO妇女的治疗进展。此外,接受环孢霉素A治疗的糖尿病患者(无论男女)均显示3α-DiolG水平升高,这种副作用导致以前无毛的区域出现了头发。