品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Biological Activity Technical DataBackground Product DatasheetsCalculators
Biological Activity
A phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC50 = 23 μM) and displays mixed agonist/antagonist actions at ERα and ERβ estrogen receptors. Converted into the anticancer agent piceatannol (Cat. No. 1554) by cytochrome P450 1B1. Activates autophagy. Also activates TRPA1 in prostate cancer-associated fibroblasts. Also SIRT1 activator.Technical Data
M.Wt:
228.25
Formula:
C14H12O3
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
501-36-0
The technical data provided above is for guidance only.For batch specific data refer to the Certificate of Analysis.Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
- Regulation of histone H2A.Z exprsesion is mediated by sirtuin 1 in prostate cancer.Baptista et al.Oncotarget, 2013;4:1673
- Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.Galluzzi et al.Nat.Rev.Drug.Discov., 2017;
- Activation of mutated TRPA1 ion channel by resveratrol in human prostate cancer associated fibroblasts (CAF).Vancauwenberghe et al.Mol.Carcinog., 2017;56:1851
- Resveratrol is a selective human cytochrome P450 1A1 inhibitor.Chun et al.Biochem.Biophys.Res.Commun., 1999;262:20
- Therapeutic potential of resveratrol: the in vivo evidence.Baur and SinclairNat.Rev.Drug Discov., 2006;5:493
- Biological effects of resveratrol.FremontLife Sci., 2000;66:663
- Resveratrol acts as a mixed agonist/antagonist for estrogen receptors α and β.Bowers et al.Endocrinology, 2000;141:3657
- Effects of stilbenes on arachidonate metabolism in leukocytes.Kimura et al.Biochim.Biophys.Acta, 1985;834:275
Product Datasheets
COA view current batch
or select another batch:
SDS
Reconstitution Calculator
Molarity Calculator
Reconstitution Calculator
Molarity Calculator
Citations for Resveratrol
The citations listed below are publications that use Tocris products.Selected citations for Resveratrol include:
7Citations: Showing 1 - 7
- Suppressive Effects of Resveratrol Treatment on The Intrinsic Evoked Excitability of CA1 Pyramidal Neurons.Authors: Meftahi Et al.Evid Based Complement Alternat Med2015;17:532
- Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress.Authors: Rojas Et al.Front Cell Neurosci2014;8:24
- Regulation of neurons in the dorsal motor nucleus of the vagus by SIRT1.Authors: Jiang and ZsombokFront Neurosci2014;7:270
- A critical role for IF. regulatory factor 9 in cerebral ischemic stroke.Authors: Chen Et al.J Neurosci2014;34:11897
- Active Constituents from Liriope platyphylla Root against Cancer Growth In Vitro.Authors: Wang Et al.Cancer Res2013;2013:857929
- SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.Authors: Pacholec Et al.J Biol Chem2010;285:8340
- Identifying the estrogen receptor coactivator PELP1 in autophagosomes.Authors: Ohshiro Et al.Br J Pharmacol2007;67:8164
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Resveratrol
There are currently no reviews for this product. Be the first toreview Resveratrol and earn rewards!
Have you used Resveratrol?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
