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VHL ligand 2 hydrochloride
Catalog Number: orb611997
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DatasheetProduct Overview
| Product Name | VHL ligand 2 hydrochloride |
|---|---|
| Catalog Number | orb611997 |
| Hazard Information | Non-Toxic |
| Target | VHL ligand 2 hydrochloride |
Product Properties
| Storage | 2 years -20°C Powder 2 weeks4°C in DMSO6 months-80°C in DMSO |
|---|---|
| Note | For research use only. |
| Purity | >98% |
| Formula | C21H18F3N5O |
| MW | 413.4 |
| CAS Number | [1948273-03-7] |
| SMILES | O=C (C1CC1)NC2=CC=CC (NC3=NC=CC (NC4=CC=CC (C (F) (F)F)=C4)=N3)=C2 |
| Chemical Name | N-[3-[[4-[[3- (trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-cyclopropanecarboxamide |
| Activity | VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. |
Product Description
VHL ligand 2 hydrochloride
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Biorbyt的mCherry。在cds质粒转染的293HEK细胞中，通过Western blot检测到一条29 kDa的条带。该抗体可很好地识别tdTomato，不识别GFP（绿色荧光蛋白）。
