Isotype: Rat IgM

Immunogen: RAW112 cells

INFORMATION: Antibody RA3-3A1 binds to an extracellular epitope of B220 (CD45R), the 220 kD variant of the T200, CD45 molecule present on B cells and B cell precursors. CD45R is implicated in a signaling pathway that involves motility and dendrite formation (2).

References:

1) Coffman RL, Weissman IL. (1981) Nature 289(5799): 681-683.

2) Partida-Sanchez S, Santos-Argumedo L, et al. (2000) Eur J Immunol 30(9): 2722-2728.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。