The human bcl-2 gene family plays a central role in lymphoid system cell survival. Continuous expression of bcl-2 protein is critical for preventing apoptosis of mature peripheral B and T cells (3).

Isotype: Murine IgG1

Immunogen: Human bcl-2 peptide 41-54 (1)

Specificity: Antibody Bcl-2/100 recognizes the human intracellular 26 kd bcl-2 protein (1, 2).

References:

1. F. Pezzella, et al, (1990) Am J Pathol 137: 225-232.

2. I.A. Doussis, et al, (1993) Am J Clin Pathol 99: 663-667.

3. S. Cory, (1995) Annu Rev Immunol 13: 513-543.

4. L Majlessi, G Bordenave (2000) Int Immunol 12(7): 969-976. https://doi.org/10.1093/intimm/12.7.969

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。