INFORMATION: Human CD66b (CEACAM8, CGMb, NCA-95, CD67) is a 95kD member of the Carcinoembryonic Antigen (CEA) group. It is expressed on granulocytes and functions as an adhesion molecule. Similar to the CD66 a, c, and d isoforms, engagement of CD66b on neutrophils causes increased adhesion to endothelial cells (2). Crosslinking CD66b on neutrophils with antibodies triggers IL-8 release (3).

References:

1) W.N. Khan, S. Hammarstrom, et al. (1992) Genomics 14(2):384-90.

2) K.M. Skubitz, A.P. Skubitz, et al. (1996) J Leuk Biol 60(1): 106-117.

3) A.K. Schroder, L Rink, et al. (2006) Human Immunol 67(9): 676-682.

Antibody from clone ANC3C5 binds to CD66b on the cell surface of humanPMN in Flow cytometry and works as an EIA capture or detection reagentfor recombinant CD66b when paired with clone ANC4A4(Cat #220-020).

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。