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Product Name | Tetramethylrhodamine - 5 - maleimide |
Size | 5 mg |
Catalog # | AS-81446 |
US$ | $254 |
Maleimides are among the most frequently used reagents for thiol modification.In most proteins, the sites of reactions are at cysteine residues that either are intrinsically present or result from reduction of cystines. Unlike iodoacetamides, maleimides do not react with histidines and methionines under physiological conditions. Tetramethylrhodamine-5-maleimide is widely used for thiol modifications of peptides and proteins. | |
Detailed Information | ![]() |
Storage | -20°C desiccated and protected from light |
References | 1. Graceffa P and Dominguez R (2003).J Biol Chem 278, 34172-80. 2. Tong Y, et al. (2001).J Gen Physiol 117, 103-18. |
Molecular Weight | 481.499 |
Molecular Formula | C28H23 N3O5 |
Spectral Properties | Abs/Em = 540/567 nm |
Solvent System | DMF or DMSO |
Product Citations | Iwamoto, M. & S. Oiki (2013). Amphipathic antenna of an inward rectifier K+ channel responds to changes in the inner membrane leaflet. PNAS 110, 749. doi: 10.1073/pnas.1217323110.Srinivasan, S. et al. (2011). L-selectin transmembrane and cytoplasmic domains are monomeric in membranes. Biochim Biophys Acta-Biomembranes doi:10.1016/j.bbamem.2011.02.006.Bakker, A. et al. (2008). Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7. PNAS 105, 3825. |