DescriptionSequence(One-Letter Code)

Product Name	IRBP, Interphotoreceptor Retinoid Binding Protein FragmentSGIPYIISYLHPGNTILHVD
Size	5 mg
Catalog #	AS-60183-5
US$	$494
Purity	% Peak Area By HPLC ≥ 95%
This 20-residue peptide, a major pathogenic T-cell epitope (161–180), is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP). It has been shown to induce posterior uveitis (EAU).
Detailed Information	Datasheet Material Safety Data Sheets (MSDS)
Storage	-20°C
References	Ref: Sonoda, K. et al. J. Immunol. 171, 2652 (2003); Read, RW. and SR. Barnum, ARVO Meeting Abstracts 43, 2281 (2002); Silver, P. et al. Invest. Ophthal. Vis. Sci. 36, 946 (1995); Karabekian, Z. et al. Invest. Ophthalmol. Vis. Sci. 46, 3769 (2005).
Molecular Weight	2209.5
SGIPYIISYLHPGNTILHVD
Sequence(Three-Letter Code)	H - Ser - Gly - Ile - Pro - Tyr - Ile - Ile - Ser - Tyr - Leu - His - Pro - Gly - Asn - Thr - Ile - Leu - His - Val - Asp - OH
Product Citations	Zhang, Z. et al. (2012). Low dose rapamycin exacerbates autoimmune experimental uveitis. Plos One doi:10.1371/journal.pone.0036589An, F. et al. Invest Ophthalmol Vis Sci 50, 3778 (2009).Tan, Jung. et al. J Immunol 178, 5578 (2007).Pennesi, G. et al. J Clin Invest 111, 1171 (2003).

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