Product Name | Glutamate Receptor Endocytosis Inhibitor, GluR23YYKEGYNVYG |
Size | 1 mg |
Catalog # | AS-62547 |
US$ | $73 |
Purity | % Peak Area By HPLC ≥ 95% |
This GluR23Y peptide was used in ELISA cell-surface assay for the insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y prevented any insulin-induced reduction. The blockade of insulin action was observed when the GluR23Y peptide was delivered into neurons by fusing it to the membrane transduction domain of HIV-1. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Ahmadian, G. et al. EMBO J. 23, 1040 (2004), Wang, D. et al. J. Biol. Chem. 279, 41267 (2004). |
Molecular Weight | 1092.2 |
YKEGYNVYG | |
Sequence(Three-Letter Code) | H - Tyr - Lys - Glu - Gly - Tyr - Asn - Val - Tyr - Gly - OH |