Product Name | Luteinizing Hormone - Releasing Hormone (LH - RH), humanPyr - HWSYGLRPG - NH2 |
Size | 25 mg |
Catalog # | AS-20782 |
US$ | $170 |
Purity | % Peak Area By HPLC ≥ 95% |
This decapeptide is a hypothalamic hormone that controls the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the pituitary gland and promotes mating behavior. It stimulates the secretion of gonadotropins after its interaction with specific G-protein-coupled receptors that are present in plasma membranes of pituitary gonadotrophs. In addition to hypophysiotropic effect, it also plays a autocrine/paracrine role in peripheral organs such as prostate, breast and ovary. Luteinizing hormone-releasing hormone is not only a neurohormone but may also function as a neurotransmitter or neuromodulator. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Kiss, J. and B. Halasz, Neurosci 14, 69 (1985); Zheng, L. et al. Neurosci 46, 407 (1992); Collado, B. et al. Intl J Oncol 24, 725 (2004); Hoffman, G. et al. Brain Res 2005 Aug 5; [Epub ahead of print]; Wang, V. et al. Am J Obstet Gynecol 160, 984 (1989). |
Molecular Weight | 1182.3 |
Pyr-HWSYGLRPG-NH2 | |
Sequence(Three-Letter Code) | Pyr - His - Trp - Ser - Tyr - Gly - Leu - Arg - Pro - Gly - NH2 |
Product Citations | Xu, Y. et al. (2010). Porous Polymer Monolithic Column with Surface-Bound Gold Nanoparticles for the Capture and Separation of Cysteine-Containing Peptides. Anal Chem 82, 3352. |