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Anaspec/Growth Hormone Releasing Factor, GRF (1 - 29), amide, human/1 mg/AS-22875

价格
¥2500.00
货号:AS-22875
浏览量:84
品牌:Anaspec
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商品描述
DescriptionSequence(One-Letter Code)
Product NameGrowth Hormone Releasing Factor, GRF (1 - 29), amide, humanYADAIFTNSYRKVLGQLSARKLLQDIMSR - NH2
Size1 mg
Catalog #AS-22875
US$$125
Purity% Peak Area By HPLC ≥ 95%

This hypophysiotropic peptide was isolated from human hypothalamic-hypophysial tissues. Within this 1 to 29 amino acid GRF fragment, amino acids 13 to 21 are more important than 24 to 29 for high affinity receptor binding. Structure–activity studies show that hpGRF(1–29)-NH2 has full intrinsic activity and potency in vitro as the full length GRF in stimulating growth hormone release. Human GRF (1-29) has a high degree (>93%) homology with procine, bovine and ovine GRF (1-29)-NH2.

Detailed InformationMaterial Safety Data Sheets (MSDS)
Storage-20°C
ReferencesLing, N. et al. Proc Natl Acad Sci USA 81, 4302 (1984)Gaudreau, P. et al. J Med Chem 35, 1864 (1992), doi: 10.1021/jm00088a023 Lance, VA. et al. Biochem Biophys Res Commun 119, 265 (1984), doi: 10.1016/0006-291X(84)91647-4 Lapierre, H. et al. Domest Anim Endocrinol 4, 207 (1987) Mayo, KE. et al. Nature 306, 86 (1983)Rivier, J. et al. Nature 300, 276 (1982), doi:10.1038/300276a0Grossman, A. et al. Clin Endocrinol (Oxf) 21, 321 (1984)
Molecular Weight3357.9
YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2
Sequence(Three-Letter Code)H - Tyr - Ala - Asp - Ala - Ile - Phe - Thr - Asn - Ser - Tyr - Arg - Lys - Val - Leu - Gly - Gln - Leu - Ser - Ala - Arg - Lys - Leu - Leu - Gln - Asp - Ile - Met - Ser - Arg - NH2
AnaSpec是一家由多肽合成、荧光标记、抗体、树脂合成专家团队组成的生物企业,为全世界的科研工作者提供全套的蛋白质组学研究解决方案。产品线主要分三个部分:多肽、检测试剂和树脂等化学试剂,适合基础研究、高通量筛选和药物发现等方面;还提供多肽合成、抗体生产和分析试剂盒开发。能合成不同数量级(mg-g级)的多种长度序列肽,常规合成肽为50个氨基酸或更长。2009年,美国Anaspec公司被Eurogentec收购