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商品描述
| Product Name | Tat - GluR23YYGRKKRRQRRRYKEGYNVYG |
| Size | 1 mg |
| Catalog # | AS-64429 |
| US$ | $113 |
The synthetic peptide (Tat-Glur23Y) contains tyrosine residues that blocks phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. Previous research shows that Tat-Glur23Y blocks regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Dalton, G. et al. Neuropsychopharma. 33, 2416 (2008); Kim, J. et al. PNAS 104, 20955 (2007). |
| Molecular Weight | 2634 |
| YGRKKRRQRRRYKEGYNVYG | |
| Sequence(Three-Letter Code) | H - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Tyr - Lys - Glu - Gly - Tyr - Asn - Val - Tyr - Gly - OH |
| Product Citations | Pauli, WM. et al. (2012). Inhibiting PKMζ reveals dorsal lateral and dorsal medial striatum store the different memories needed to support adaptive behavior. Learn Mem 19, 307.Li, Y. et al. (2011). Inhibition of PKMζ in nucleus accumbens core abolishes long-term drug reward memory. J Neurosci 31, 5436. |
