Product Name | Aminopeptidase N Ligand (CD13), NGR peptideCNGRCG (Disulfide bridge: 1 - 5) |
Size | 5 mg |
Catalog # | AS-60171-5 |
US$ | $504 |
The NGR (Asn-Gly-Arg) peptide motif is an aminopeptidase N (CD13) ligand that targets angiogenic blood vessels. NGR-containing peptides have been proven useful for delivering cytotoxic drugs, proapoptotic peptides and tumor necrosis factor (TNF) to tumor vasculature. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Ref: Curnis, F. et al. Cancer Res. 62, 867 (2002); Curnis, F. et al. J. Clin. Invest. 110, 475 (2002). |
Molecular Weight | 606.7 |
CNGRCG (Disulfide bridge: 1-5) | |
Sequence(Three-Letter Code) | H - Cys - Asn - Gly - Arg - Cys - Gly - OH (Disulfide bridge: 1 - 5) |
Product Citations | Bartz, R. et al. (2011). Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape. Biochem J doi:10.1042/BJ20101021. |